Consulting a Healthcare Professional About ED

Because the drug acts on arteries beyond the penis, it can produce various side effects. That means it should only be prescribed by a personal physician who really knows you. And it also means that scientists are investigating uses for the drug in patients with an array of vascular disorders having nothing to do with sexual function. They have nearly identical effects on ED as well as similar side effects. Because they are newer drugs, scientists are just beginning to study them for problems that don't involve sexuality.

What is Viagra?

Sildenafil was discovered by scientists looking for a new medication to dilate coronary arteries. It does that, but because it widens healthy coronary arteries more than diseased vessels, it has not been successful in treating angina. But it may have other benefits for cardiac patients. In the first years of the Viagra era, research on sildenafil and the heart was devoted to making sure the drug was safe for the circulation. In most men with heart disease, it is.

Can you become dependent on Viagra?

But several studies of patients with congestive heart failure also reported that the medication improves oxygen consumption, pulmonary artery pressure, and exercise capacity in these patients. Research shows that sildenafil helps the heart muscle relax properly, which could help patients with heart failure due to diastolic dysfunction. Another interesting property is sildenafil's ability to protect the heart from excessive stimulation by adrenaline. Clinical trials will be needed to see which patients might benefit. It's the most speculative use for sildenafil, and it's far from clinical application. Sildenafil has already been licensed to treat men and women with pulmonary hypertension. Time will tell if any of these drugs will fill other potentials beyond promoting potency.

Brand Name	Onset Time (min)	Duration (hours)	Food Interaction	Notes
Viagra	30-60	4-6	Delayed with high-fat meals	Commonly used for ED
Kamagra	30-45	4-6	Less affected by food	Cheaper alternative
Caverta	30-60	4-6	Take on empty stomach	Available in generic
Revatio	40-60	4-6	Similar to Viagra	Prescribed for pulmonary hypertension

Safety is a key factor to consider before using any medication, and treatments for erectile dysfunction (ED) are no exception. Luckily, ED is a treatable issue with several well-known options, such as sildenafil (the active ingredient in Viagra®), tadalafil (Cialis®), and newer ED treatments, such as avanafil (Stendra®).

Product	Dosage	Quantity + Bonus	Price
Viagra Original	100mg	14 + 2 Pills	89.03€ 84.79€	Buy
Viagra Generic	150mg	90 + 6 Pills	147.18€ 140.17€	Buy
Viagra Generic	50mg	120 + 6 Pills	129.64€ 123.47€	Buy
Viagra Oral Jelly	100mg	21 Sachets	78.66€ 74.91€	Buy
Viagra Generic	200mg	20 Pills	61.69€ 58.75€	Buy
Viagra Oral Jelly	100mg	63 + 7 Sachets	190.54€ 181.47€	Buy
Viagra Generic	150mg	270 + 10 Pills	326.61€ 311.06€	Buy
Viagra Generic	25mg	360 + 10 Pills	213.68€ 203.50€	Buy
Viagra Super Active	100mg	180 + 20 Pills	280.97€ 267.59€	Buy
Viagra Generic	200mg	30 + 2 Pills	83.07€ 79.11€	Buy
Viagra Generic	50mg	20 Pills	40.52€ 38.59€	Buy
Viagra Generic	200mg	90 + 6 Pills	170.79€ 162.66€	Buy
Viagra Original	100mg	64 + 4 Pills	264.15€ 251.57€	Buy
Viagra Generic	25mg	30 + 4 Pills	47.97€ 45.69€	Buy
Viagra Soft Tabs	100mg	60 + 6 Pills	152.94€ 145.66€	Buy
Viagra Original	100mg	34 + 2 Pills	163.67€ 155.88€	Buy

The United States Food and Drug Administration (FDA) approves all of these medications. All of the FDA-approved ED medications on the market right now are safe for most men to use regularly.

Frequently Asked Questions:

The animals who got sildenafil recovered better, with the highest doses producing the best results. The scientists concluded that the medication actually stimulated the growth of new nerve cells in the brain tissue next to the stroke damage. It's far too early to know whether sildenafil may someday help people with strokes. If you get your information about sildenafil from Super Bowl commercials or e-mail spam, you might dismiss it as a lifestyle drug of little real medical importance. In fact, it's a serious prescription medication that has helped millions of men who are distressed by an entirely legitimate medical problem. However, there are some side effects and drug interactions that you should be aware of before taking any medication for ED. These side-effect rates can differ from one drug to another, meaning one may be a more effective option for you than its alternatives depending on your personal needs and health profile.

Proper Use

Still, it's an interesting area of new research. A European study of 25 men who had erectile dysfunction but no other circulatory disorders found that blood vessels in the brain responded to stress better after a 50-mg dose of sildenafil. More interesting results were reported by scientists in Michigan, who produced ischemic strokes in rats by temporarily blocking blood vessels. During their recovery, the animals were divided into three groups. One received no treatment, another low-dose sildenafil, and the third high-dose sildenafil. Below, we’ve explained how ED medications work, their potential side effects, and other key safety data that you should be aware of before using any medication to treat ED. Erectile dysfunction is a common form of sexual dysfunction that affects an estimated 30 to 50 million men in the United States alone. Studies estimate that as many as 40 percent of all men will deal with some level of erectile dysfunction by the age of 40 — and that rate only increases with age. But certain treatments can viagra cream help manage the condition’s key symptoms. Erectile dysfunction medication has been around since the late 1990s, when the FDA approved Viagra as the first pill for treating ED (here is a guide on where to buy Viagra).

Related/similar drugs

But since it's a serious problem, any benefit is most welcome. When we think of blood pressure, we usually think of the systemic circulation, of the blood pumped from the heart's left ventricle to the aorta and then to the smaller arteries that carry oxygen-rich blood throughout the body. But to pick up vital oxygen, blood must first pass from the less powerful right ventricle through the pulmonary artery to the lungs, then back to the left side of the heart. The pressures in the pulmonary artery are much lower (about 20/10 millimeters of mercury, or mm Hg) than in the aorta (lower than 120/80 mm Hg is considered healthy). Exercise is the most common cause of rising pulmonary artery pressure, but the elevation is mild and subsides promptly with rest.

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High altitudes are another cause, which can lead to mountain sickness (see below). Far more serious are the large number of lung diseases, vascular diseases, heart disorders, and miscellaneous conditions that can cause pulmonary hypertension. And in primary pulmonary hypertension, no underlying cause is evident. Pulmonary hypertension causes shortness of breath, first during exertion but eventually at rest if the condition progresses. A variety of treatments are available, depending on the underlying problem. Currently, there are four FDA-approved oral medications for ED: The active ingredient in Viagra, sildenafil, is the most well-known medication for erectile dysfunction.

The Best Type of Viagra?

And the FDA has approved sildenafil (Revatio) in a dose of 20 mg three times a day for men and women with pulmonary hypertension. Clinical trials have demonstrated improved exercise tolerance with few side effects. Pulmonary hypertension is a feature of acute mountain sickness. High altitudes produce low blood-oxygen levels. In turn, low oxygen produces a narrowing of the pulmonary arteries.

Your expert team

The heart must therefore work harder, reducing the capacity to exercise. To find out if it might improve exercise capacity in low oxygen conditions, scientists tested 14 healthy mountain climbers in a lab in Germany and again at a Mount Everest base camp. In the lab, the volunteers breathed 10% oxygen through a mask; on the mountain, they breathed natural air. Under both conditions, a 50-mg sildenafil tablet decreased pressures in the lungs' blood vessels and increased the maximum exercise capacity. It's a small study, and it's too soon to say if sildenafil will help prevent or treat acute mountain sickness. It’s designed for use at least one hour before sex and works for about four hours per dose. Sildenafil is available as the brand-name Viagra and as a generic version. It’s a popular choice that works well for most men affected by ED.

Popular FAQ

Still, a study of 29 climbers reported that tadalafil can also reduce pulmonary artery pressure at a high altitude. In affected individuals, exposure to the cold triggers spasm of the small arteries that supply blood to the fingers, toes, or both. Temporarily deprived of adequate blood flow, the involved digits become pale, cold, and very painful. It's a common condition, affecting up to 8% of men and 17% of women. In the vast majority, there are no underlying diseases (primary Raynaud's), and patients do well simply by minimizing their exposure to cold.

Heart health and erectile dysfunction

But secondary Raynaud's can complicate collagen-vascular diseases or certain other conditions. It's not common, but secondary Raynaud's viagra black can be very painful and difficult to treat. Many medications have been used without consistent success. But a 2005 study of 16 patients with severe Raynaud's phenomenon that had not responded to other medications reported benefit from sildenafil in a dose of 50 mg twice a day. And a 2006 study of 40 Raynaud's patients reported similar benefits from vardenafil in a dose of 10 mg twice a day. The active ingredient in Viagra, sildenafil, is the most well-known medication for erectile dysfunction. The active ingredient in Cialis®, tadalafil, is an ED drug that offers relief for up to 36 hours per dose. This long duration of action has earned it the nickname, the “weekend pill.” Tadalafil is available as the brand-name Cialis and as a generic medication. It can be used as needed before sexual activity or taken daily at a reduced dosage to provide ongoing ED relief.

Country	Viagra (per pill)	Kamagra (per pill)	Caverta (per pill)	Revatio (per pill)	Notes
USA	$20 - $25	$5 - $15	$15 - $20	$20 - $30	Brand and pharmacy dependent
India	$1 - $3	$1 - $2	$1 - $3	$5 - $10	Cheaper generics available
UK	£15 - £20	£3 - £8	£12 - £18	£18 - £25	Prescription required
Australia	AU$20 - AU$30	AU$5 - AU$12	AU$16 - AU$22	AU$25 - AU$35	Higher cost overall

The active ingredient in Levitra®, vardenafil, works similarly to sildenafil but has a slightly longer half-life. This means it remains active in the body for longer. It’s only available as a generic medication. The active ingredient in Stendra®, avanafil, is a second-generation medication for ED. It’s more selective in its effects than older ED drugs and starts working in as little as 15 minutes.

Brand Name	Alcohol Interaction	Food Interaction	Best Time to Take	Tips
Viagra	Moderate interaction	High-fat meals delay onset	1 hour before activity	Maximize effectiveness
Kamagra	Similar to Viagra	Less affected by food	30-60 min before	Avoid excessive alcohol
Caverta	Moderate interaction	Best taken on empty stomach	30 min beforehand	Check for food effects
Revatio	Similar to Viagra	No significant food interaction	1 hour prior	Monitor alcohol intake

It’s also less likely to cause some side effects. Currently, it’s only available as the brand-name medication, with no generic option available for sale.

• Cialis (Tadalafil): Alternative to Viagra, lasts up to 36 hours, allows for more spontaneity, needs proper medical consultation.
• Levitra (Vardenafil): Works in about 25 minutes, effective for 4-5 hours, suitable for men with certain health conditions.
• Staxyn (Vardenafil ODT): Orally disintegrating tablet, no water needed, quick onset, convenient for on-the-go use.

Other ED medications exist besides these oral ones.

• VibraPlus: Herbal, natural formula aiming to enhance stamina and erection quality, caution advised for unproven claims.
• MaxMan: Dietary supplement designed for libido boost, not a direct ED treatment, use with medical advice.
• Max Performer: Nutritional supplement, claimed to support erectile health, but evidence for effectiveness is limited.

Alprostadil (Caverject®) is an FDA-approved medication for ED that can be injected or used inside the urethra. Compounded medications like BiMix, TriMix, and QuadMix can also be used for ED and are given by injection or in the urethra—but know that compounded medications are not FDA-approved. All four of the oral medications listed above belong to a class of drugs called PDE5 inhibitors. These medications work by inhibiting the effects of the enzyme phosphodiesterase type 5 (PDE5). This enzyme breaks down a signaling molecule called cyclic guanosine monophosphate (cGMP), which plays a key role in relaxing smooth muscles and regulating blood flow to the erectile tissue of the penis.