The Science Behind Dapoxetine's Mechanism of Action

Remind any doctor, dentist or pharmacist you visit that you are taking PRILIGY. Keep all of your doctor's appointments so that your progress can be checked. Talk to your doctor before you stop taking this medicine. You may have problems sleeping and feel dizzy after you stop taking it, even if you have not taken it every day. Do not take PRILIGY to treat any other complaints unless your doctor tells you to. Do not give your medicine to anyone else, even if they have the same condition as you. Be careful before you drive or use any machines or tools until you know how PRILIGY affects you.

2. What should I know before I take PRILIGY?

These medicines may be affected by PRILIGY or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines. Other medicines not listed here may be affected by PRILIGY or may affect how well it works. Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine. The recommended dose is one tablet (30mg), taken when you need it, about 1 to 3 hours before sexual activity.

When to take PRILIGY

Do not take more than one tablet once every 24 hours due to increased risk of side effects and lack of additional benefit. Swallow the tablet whole to avoid a bitter taste, with at least one full glass of water. PRILIGY may be taken with or without food. Do not drink grapefruit juice within 24 hours prior to taking PRILIGY. Grapefruit juice can increase the level of this medicine in your body.

Generic Names

PRILIGY should be taken as needed, when sexual activity is anticipated. As PRILIGY is only taken when needed, it is not a problem if you forget to take it. Tell your doctor or pharmacist if you have taken more PRILIGY tablets than you should. Symptoms of overdose in PRILIGY are drowsiness, nausea, vomiting, rapid heartbeat, tremor, agitation and dizziness. If you think that you have taken too much PRILIGY, you may need urgent medical attention. This medicine may cause dizziness, light-headedness, tiredness, drowsiness, fainting, having difficulty concentrating and blurred vision in some people. If you have any of these symptoms, do not drive, operate machinery or do anything else that could be dangerous. Avoid alcohol while you are taking this medicine.

Product	Dosage	Quantity + Bonus	Price
Viagra Super Active	100mg	270 + 30 Pills	390.61€ 372.01€	Buy
Priligy Generic Dapoxetine	60mg	90 + 10 Pills	265.64€ 252.99€	Buy
Cialis Professional	40mg	20 Pills	110.24€ 104.99€	Buy
Kamagra Soft Tabs	100 mg	272 + 12 Pills	593.42€ 565.16€	Buy
Cialis Generic	10mg	60 + 6 Pills	105.81€ 100.77€	Buy
Kamagra	100mg	12 Pills	55.64€ 52.99€	Buy
Cialis Generic	40mg	180 + 10 Pills	277.29€ 264.09€	Buy
Priligy Generic Dapoxetine	60mg	120 + 10 Pills	341.26€ 325.01€	Buy
Priligy Generic Dapoxetine	60mg	180 + 10 Pills	494.76€ 471.20€	Buy
Priligy Generic Dapoxetine	60mg	30 + 6 Pills	106.65€ 101.57€	Buy
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Cialis Super Active	20mg	90 + 10 Pills	314.14€ 299.18€	Buy

The effects of alcohol, such as dizziness, drowsiness, slow reflexes or impaired judgement, may be increased if taken with PRILIGY. Follow the instructions on the carton on how to take care of your medicine properly.

Usage Instructions

It is important you understand these risks and how to monitor for them. PRILIGY has been studied for use by men with premature ejaculation. Its safety in women has not been established. Do not take PRILIGY if you are under 18 years of age, or over 65 years of age. Safety and effectiveness in patients under 18 years or over 65 years have not been established.

Better Timing Control

This medicine contains lactose (a type of sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine. Tell your doctor or pharmacist if you are taking any other medicines, including any medicines, vitamins or supplements that you buy without a prescription from your pharmacy, supermarket or health food shop. Some medicines and PRILIGY may interfere with each other. linezolid, an antibiotic used to treat infection tryptophan, used to help your mood and help you sleep St John's wort (Hypericum perforatum), a herbal preparation.

Drinking alcohol

PRILIGY should not be taken with the above listed medicines/ herbal preparations or within 14 days of stopping these medicines. Once you stop taking PRILIGY you will need to wait 7 days before taking these medicines/ herbal preparations. Other medicines or food and PRILIGY may interfere with each other. medicines for mental health problems other than depression medicines to thin your blood, such as warfarin certain medicines for fungal infections, including ketoconazole, itraconazole and fluconazole certain medicines for HIV, including ritonavir, saquinavir and atazanavir certain medicines used to treat high blood pressure and chest pain (angina), enlarged prostate, or erectile dysfunction (impotence), as these medicines may lower your blood pressure, possibly upon standing anti-inflammatory medicines such as ibuprofen or aspirin certain antibiotics for treating infection, such as erythromycin, telithromycin and clarithromycin Do not drink grapefruit juice within 24 hours prior to taking PRILIGY narcotics (strong pain medicines) or benzodiazepines such as valium. Check with your doctor or pharmacist if you are not sure about what medicines, vitamins or supplements you are taking and if these affect PRILIGY. Keep your tablets in the pack until it is time to take them. If you take the tablets out of the pack they may not keep well. Store it in a cool dry place below 25°C and away from moisture, heat or sunlight; for example, do not store it: in the bathroom or near a sink, or in the car or on window sills. Heat and dampness can destroy some medicines. Keep it where young children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines. If you no longer need to take this medicine or it is out of date, take it to any pharmacy for safe disposal. Do not use this medicine after the expiry date.

• Discontinuation rates in studies are often due to side effects.
• Nausea is the most common reason for stopping.
• Taking the tablet with a light snack may reduce nausea.
• Dizziness can be mitigated by rising slowly from sitting.
• Headaches may be managed with simple analgesics.
• If side effects are intolerable, the drug should be stopped.
• A lower dose is not available below 30mg.
• Therefore, discontinuation is the only option if 30mg is not tolerated.
• Most side effects are mild to moderate and transient.
• They often diminish with continued use.
• However, continued use does not mean daily use.
• Tolerance to the therapeutic effect does not develop.

If you do experience any side effects, most of them are minor and temporary. However, some side effects may need medical attention. See the information below and, if you need to, ask your doctor or pharmacist if you have any further questions about side effects. Tell your doctor or pharmacist if you notice anything else that may be making you feel unwell.

1. Why am I taking PRILIGY?

You have not had water to drink in the past 4 to 6 hours You have been sweating for a long time You have an illness where you have a high temperature, diarrhoea or being sick If you feel like you might faint (such as feeling sick, feeling dizzy, light-headed, feeling weak, confused, sweaty or an abnormal heart beat), or feel light-headed when you stand up, immediately lie down so your head is lower than the rest of your body or sit down with your head between your knees until you feel better. This will stop you from falling and hurting yourself if you do faint. Do not stand up quickly after you have been sitting or lying down for a long time. Do not drive or use any tools or machines if you feel faint when taking this medicine. Tell your doctor if you faint when taking this medicine. Other side effects not listed here may occur in some people. After you have received medical advice for any side effects you experience, you can report side effects to the Therapeutic Goods Administration online at By reporting side effects, you can help provide more information on the safety of this medicine. Always make sure you speak to your doctor or pharmacist before you decide to stop taking any of your medicines. This medicine is only available with a doctor's prescription. This medicine does not contain sucrose, gluten, tartrazine or any other azo dyes.

• It is important to distinguish PE from other dysfunctions.
• Rapid ejaculation with loss of erection may indicate ED.
• A thorough medical and sexual history is critical.
• Physical examination may rule out anatomical issues.
• Laboratory tests are not routinely required.
• Thyroid function tests may be done if symptoms suggest.
• Neurological examination is rarely needed.
• The condition is common, affecting 20-30% of men.
• Despite being common, many men do not seek help.
• Stigma remains a significant barrier to treatment.
• Dapoxetine's approval helped legitimize PE as a treatable condition.
• Public awareness campaigns aim to reduce stigma.

Do not take this medicine if you are allergic to any of these ingredients. PRILIGY 30 mg film-coated tablets are light grey, round and marked "30" inside a triangle on one side (AUST R 147946).

Interacting Drug/Class	Effect on Dapoxetine	Potential Risk
CYP3A4 inhibitors	Increased plasma levels	Greater side effect risk
SSRIs	Serotonin syndrome risk	Use cautiously or avoid combination
Alcohol	Increased sedative effects	Impairment and risk of dizziness

PRILIGY is supplied in blister packs containing 3 or 6 tablets.

Possible Side Effects

phone the Poisons Information Centre (by calling 13 11 26), or go to the Emergency Department at your nearest hospital. You should do this even if there are no signs of discomfort or poisoning. WARNING: PRILIGY can make you faint or make you feel dizzy or light-headed. To help lower the chance of this happening: Take PRILIGY with at least one full glass of water. Do not take PRILIGY if you are dehydrated (you do not have tadalafil dapoxetine enough water in your body). This leaflet was prepared in March 2024. Priligy is the brand name for dapoxetine, a medication approved for the treatment of premature ejaculation in men.

Why Many Men Prefer the 30mg Strength First

you are prone to fainting or passing out caused by a temporary drop in blood pressure (Syncope). Before you start taking this medicine, your doctor should perform a test to make sure that your blood pressure doesn’t drop too much when you stand up from sitting or lying down. you have not been diagnosed with premature ejaculation you use recreational drugs such as ecstasy or LSD (lysergic acid diethylamide). Taking PRILIGY with these drugs can cause serious reactions. you take narcotics (strong pain medicines) or benzodiazepines such as Valium.

Who distributes PRILIGY

These medicines can increase the drowsiness and dizziness of PRILIGY. Alcohol can increase the risk of fainting and should be avoided while taking PRILIGY. you are currently using medications to treat fungal infections you are currently taking medicine that thins your blood such as aspirin, anticoagulants such as warfarin, non-steroidal anti-inflammatory medicines (NSAIDs) such as ibuprofen, or medicine used to treat psychiatric conditions such as depression. Taking PRILIGY together with these medications can increase the risk of bleeding abnormalities. you have a history of dizziness from low blood pressure you have or have had heart and blood vessel problems you have a history of bleeding or blood clotting problems you have or have had any thoughts of suicide or harming yourself.

Depression and anxiety

All thoughts of suicide must be taken seriously. Tell your doctor or a mental health professional immediately if you have any suicidal thoughts or other mental/mood changes. you have or have had psychiatric disorders, such as schizophrenia you have history of mania (great excitement, hallucinations, difficulty in concentrating or staying still) or bipolar disorder (extreme mood swings between mania and depression) or develop these disorders you have or have had seizures (fits) or have uncontrolled epilepsy you have moderate or severe liver problems you have or have had other forms of sexual problems such as erectile dysfunction. It is not known whether PRILIGY can worsen these conditions. you have eye problems such as glaucoma, (high pressure in the eye ) During treatment, you may be at risk of developing certain side effects.