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Talk to your health care provider about PrEP or use the HIV Services Locator to find a provider near you.

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PrEP, or pre-exposure prophylaxis, is medicine people at risk for HIV take to prevent getting HIV from sex or injection drug use. PrEP can stop HIV from pills to get her in the mood instantly taking hold and spreading throughout your body. Currently, there are two FDA-approved daily oral medications for PrEP. There are also two FDA-approved long-acting injectable forms of PrEP, one that is administered every other month and the other is administered twice yearly. PrEP is highly effective at preventing HIV when taken as indicated. PrEP reduces the risk of getting HIV from sex by about 99% when taken as prescribed. Among people who inject drugs, it reduces the risk by at least 74% when taken as prescribed. PrEP is much less effective when it isn't taken consistently. PrEP may benefit you if you test negative for HIV and any of the following apply to you: you have had anal or vaginal sex in the past 6 months, and you: have a sexual partner with HIV (especially if the partner has an unknown or detectable viral load), or have not consistently used a condom, or have been diagnosed with an STD in the past 6 months. have an injection partner with HIV, or share needles, syringes, or other injection equipment.

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Breaking Barriers in Prostate Cancer CareProstate Cancer and Health EquityLearn about prostate cancer disparities in Black men and how screening, access to care, and advocacy can make a difference. Learn about prostate cancer disparities in Black men and how screening, access to care, and advocacy can make a difference. Digestive HealthElizabeth Ward, RD, MSRegistered dietitian nutritionist Skin CareMary Alice Mina, MDDouble board-certified dermatologist As a leader in digital health publishing for more than 25 years, WebMD strives to maintain the most comprehensive and reliable source of health and medical information on the internet. We recognize the responsibility that comes along with being the most well-known and trusted health information platform — and we take that responsibility seriously by: 01Charging our content creators to practice journalistic principles of excellence and provide objective, accurate, and balanced reporting 02Maintaining editorial independence and transparency into how we protect the integrity of our content 03Regularly reviewing and updating our content by working with our network of more than 100 doctors and health experts Pre-exposure prophylaxis, also called PrEP, is a safe, effective prescription medicine that can reduce the risk of getting HIV by as much as 99%. PrEP may be right for you if you test negative for HIV and have certain other risk factors. you’ve been prescribed PEP (post-exposure prophylaxis) and youreport continued risk behavior orhave used multiple courses of PEP You may choose to take PrEP even if the behaviors above don’t apply to you. If you have a partner with HIV and are considering getting pregnant, talk to your doctor about PrEP. PrEP may be an option to help protect you and your baby from getting HIV while you try to get pregnant, during pregnancy, or while breastfeeding.

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There are two pills approved for daily use as PrEP.

Ingredient Type Examples Typical Benefits Potential Risks
Natural Ginseng, Horny Goat Weed, Maca Fewer side effects, hormone balance Allergies, inconsistent potency
Synthetic Sildenafil, Tadalafil (prescription) Stronger immediate effect More side effects, legal issues
Herbal Extracts Tribulus Terrestris, Epimedium Improved libido and stamina Possible interactions with meds
Amino Acids L-Arginine, L-Citrulline Better blood flow, nitric oxide boost Overdose risk if misused

They are combinations of two anti-HIV drugs in a single pill: Truvada® (emtricitabine/tenofovir disoproxil fumarate) is for all people at risk for HIV through sex or injection drug use.

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Descovy® (emtricitabine/tenofovir alafenamide) is for sexually active men at risk of getting HIV.

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Before Addyi, there were 26 FDA-approved treatments for male sexual dysfunction. Not because the need wasn’t there. But because there was simply no desire to take women’s desire seriously. Your online visit today is only $49 $19. By clicking here you will go to a third-party telemedicine provider.

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See full prescribing Information including Boxed Warning regarding severe low blood pressure and fainting in certain settings at addyi.com/pi Your online visit today is only $49 $19. What is the most important information I should know about ADDYI? ADDYI can cause severe low blood pressure and fainting (loss of consciousness). Your risk is higher if you drink alcohol close to your dose. Do not take ADDYI with certain medicines or if you have liver problems. Descovy® is not for women who are at risk for HIV through receptive vaginal sex. Two long-acting injectable forms of PrEP have also been approved by the FDA: Apretude® (cabotegravir) is for adults and adolescents at risk for HIV through sex who weigh at least 77 pounds (35 kg). It’s an injection given by your health care provider every other month instead of daily oral pills. Yeztugo® (lenacapavir) is for adults and adolescents at risk of HIV through sex who weigh at least 77 pounds (35 kg). It is an injection given by your health care provider twice yearly instead of daily pills. The starter dose includes oral pills taken for the first two days to get the medication concentration in the body up to protective levels quickly. No significant health effects have been seen in people who are HIV-negative and have taken PrEP for up to 5 years. Some people taking PrEP may have side effects, like nausea, diarrhea, headache, fatigue, and stomach pain.

What Drugs Are Approved for PrEP?

ADDYI can cause serious side effects, including: See “What is the most important information I should know about ADDYI?” This is not a complete list of side effects. ADDYI is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in women < 65 years of age who have not had problems with low sexual desire in the past, no matter the type of sexual activity, situation, or sexual partner, and it is troubling to them. Their low sexual desire is not due to a medical or mental health problem, problems in the relationship, medicine or other drug use. ADDYI is not for use in men or to improve sexual performance. 10 Ways to Lower Prescription and Treatment CostsThe costs for every aspect of health care are at an all-time high – and rising.

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Take these steps to make sure you get the most from every dollar you spend. The costs for every aspect of health care are at an all-time high – and rising. Cost-Saving Tips From an Efficiency Expert A Caregiver's Guide to Managing Medical Expenses A New Once-Daily Pill for Weight LossThis daily GLP-1 tablet offers an effective oral option for managing obesity. Clinical studies show it leads to significant weight loss and improved metabolic health. This daily GLP-1 tablet offers an effective oral option for managing obesity. These side effects are usually not serious and go away over time. If you are taking PrEP, tell your health care provider if you have any side effect that bothers you or that does not go away. And be aware: PrEP protects you against HIV but not against other sexually transmitted infections (STIs) or other types of infections. Combining PrEP with condoms will reduce your risk of getting other STIs. If you think PrEP may be right for you, visit your doctor or health care provider. Any health care provider licensed to write prescriptions can prescribe PrEP; specialization in infectious diseases or HIV medicine is not required.

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Because PrEP is for people who are HIV-negative, you’ll have to get an HIV test before starting PrEP and you may need to get other tests to make sure it’s safe for you to use PrEP. If you take daily oral PrEP, you’ll need to see a health care provider every 3 months for repeat HIV tests, prescription refills, and follow-up.

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If you use injectable PrEP, you’ll need to see a healthcare provider every two or six months for an HIV test and the injections, depending on which option you chose. If you don’t have a health care provider: You can use the HIV Services Locator to find a PrEP provider and other HIV services near you. You can visit many community health centers for PrEP services.

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To lower your risk of low blood pressure and fainting: Do not drink alcohol close to the time you take ADDYI. Skip your dose if you had 3 or more drinks before bedtime. Wait at least 2 hours after 1–2 alcoholic drinks before taking ADDYI. After taking ADDYI, do not drink alcohol until the next day Talk to your doctor about the medicines and supplements you take and before starting any new ones Do not take ADDYI if you have liver problems If you feel dizzy or lightheaded after taking ADDYI, lie down right away. Get medical help if symptoms do not go away.

Regional issues

take certain medicines that increase ADDYI levels in your blood (including some treatments for HIV, fungal infections, antibiotics, hepatitis C, heart conditions, or depression such as nefazodone) What should I tell my doctor before taking ADDYI? Tell your doctor about all your medical conditions, including if you: drink alcohol, use drugs, or have a history of substance abuse have ever had depression or other mental health conditions have low blood pressure or a condition that can cause it Tell your doctor or pharmacist about all medicines and supplements you take, as they may interact with ADDYI. What should I avoid while taking ADDYI? Do not drink alcohol close to your dose Do not drive or operate machinery for at least 6 hours after taking ADDYI Do not take supplements such as St. John’s Wort, ginkgo, or resveratrol, or certain medicines like cimetidine, without talking to your doctor What are the possible side effects of ADDYI?

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